Motif ID: FOX{C1,C2}.p2

Z-value: 0.485


Transcription factors associated with FOX{C1,C2}.p2:

Gene SymbolEntrez IDGene Name
FOXC1 2296 forkhead box C1
FOXC2 2303 forkhead box C2 (MFH-1, mesenchyme forkhead 1)

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
FOXC1chr6_+_1610680-0.251.8e-01Click!
FOXC2chr16_+_86600856-0.154.4e-01Click!


Activity profile for motif FOX{C1,C2}.p2.

activity profile for motif FOX{C1,C2}.p2


Sorted Z-values histogram for motif FOX{C1,C2}.p2

Sorted Z-values for motif FOX{C1,C2}.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of FOX{C1,C2}.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chrX_-_63450486 0.682 NM_130388
ASB12
ankyrin repeat and SOCS box containing 12
chr8_-_27115935 0.593 STMN4
stathmin-like 4
chr21_-_43735462 0.580 TFF3
trefoil factor 3 (intestinal)
chr3_+_133495925 0.548 TF
transferrin
chr10_+_7745341 0.544 ITIH2
inter-alpha-trypsin inhibitor heavy chain 2
chr10_+_7745354 0.542 ITIH2
inter-alpha-trypsin inhibitor heavy chain 2
chr10_-_13276327 0.519 NM_145314
UCMA
upper zone of growth plate and cartilage matrix associated
chr10_+_7745325 0.507 ITIH2
inter-alpha-trypsin inhibitor heavy chain 2
chr5_+_140165875 0.474 NM_018900
NM_031410
NM_031411
PCDHA1


protocadherin alpha 1


chr7_-_99573637 0.471 NM_001185
AZGP1
alpha-2-glycoprotein 1, zinc-binding
chr21_+_43823970 0.447 NM_001001895
NM_001243467
NM_018961
UBASH3A


ubiquitin associated and SH3 domain containing A


chr2_-_119605758 0.440 NM_001426
EN1
engrailed homeobox 1
chr12_-_25706177 0.438 NM_152590
NM_001145728
NM_001145729
IFLTD1


intermediate filament tail domain containing 1


chr12_+_69742130 0.431 NM_000239
LYZ
lysozyme
chr10_+_96522457 0.429 NM_000769
CYP2C19
cytochrome P450, family 2, subfamily C, polypeptide 19
chr20_-_44175995 0.422 NM_001198986
NM_020398
SPINLW1-WFDC6
SPINLW1
SPINLW1-WFDC6 readthrough
serine peptidase inhibitor-like, with Kunitz and WAP domains 1 (eppin)
chr10_+_7745229 0.413 NM_002216
ITIH2
inter-alpha-trypsin inhibitor heavy chain 2
chr4_+_71494460 0.407 NM_031889
ENAM
enamelin
chr20_+_9198036 0.403 NM_182797
PLCB4
phospholipase C, beta 4
chr12_+_69742140 0.396 LYZ
lysozyme

Gene Ontology Analysis

Nothing significant found in process category.

Gene overrepresentation in compartment category:

Showing 1 to 11 of 11 entries
enrichment   p-value GO term description
25.78 2.68e-02 GO:0030868 smooth endoplasmic reticulum membrane
2.81 8.04e-03 GO:0005578 proteinaceous extracellular matrix
2.74 3.19e-03 GO:0031012 extracellular matrix
1.89 1.97e-03 GO:0005887 integral to plasma membrane
1.86 3.29e-03 GO:0031226 intrinsic to plasma membrane
1.82 3.71e-02 GO:0044421 extracellular region part
1.74 2.23e-04 GO:0005576 extracellular region
1.69 3.98e-04 GO:0044459 plasma membrane part
1.51 1.86e-05 GO:0071944 cell periphery
1.48 1.44e-04 GO:0005886 plasma membrane
1.25 4.64e-02 GO:0044425 membrane part

Gene overrepresentation in function category:

Showing 1 to 6 of 6 entries
enrichment   p-value GO term description
8.60 1.12e-03 GO:0003823 antigen binding
3.94 1.97e-02 GO:0046906 tetrapyrrole binding
1.75 2.88e-03 GO:0004872 receptor activity
1.74 4.54e-02 GO:0004888 transmembrane receptor activity
1.63 7.01e-03 GO:0004871 signal transducer activity
1.63 7.01e-03 GO:0060089 molecular transducer activity